Latest research on Neomycin Sulfate

A component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed). Neomycin is a bactericidal aminoglycoside antibiotic that binds to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and acceptor tRNA sites and results in the production of non-functional or toxic peptides.

Latest findings

The animals are unilaterally deafened by infusing an ototoxic compound (Neomycin Sulfate) into the inner ear to damage the sensory hair cells and initiate a secondary degeneration of the spiral ganglion neurons. [source, 2015]
This study, the largest population-level analysis of the intestinal resistome to date, also showed that the abundance of Antibiotic resistance genes (ARGs) is highest for Antibiotics that have been longer in the market and for those approved for animal use, such as TETRACYCLINE, Bacitracin and the cephalosporins. [source, 2016]
In HCs, the thresholds were <40 dB SPL before the animals were deafened by slow instillation of 300 ┬ÁL of Neomycin Sulfate into the scala tympani (within 5 min). [source, 2016]
The compounds and concentrations used were the following: Amphotericin B (30 mM), benomyl (25 mM), geneticin (10 mM), Menadione (10 mM), hygromycin B (50 mM), latrunculin B (2.5 mM), myriocin (12.5 mM), miconazol (50 mM), Rapamycin (2.5mM), tunicamycin (10 mM), Cyclosporine A (50 mM), Hydroxyurea (50 mM), orthovanadate (50 mM) and Neomycin Sulfate (100 and 200 mM). [source, 2016]
Previously, hygromycin B, Neomycin Sulfate or Rapamycin were added in two-fold serial dilutions to the plates. [source, 2016]
As a result, we found that expression of GFP-AnkB, but not the other effectors, affected yeast sensitivity to aminoglycosides, like Neomycin Sulfate and hygromycin B (Fig 8A). [source, 2016]
To develop the reporter system, a stable clone of double-transfected HA-TSHR and CRE luciferase (HATSHR-Luci#1) cells was selected from several double-transfected clones using high concentrations of Neomycin Sulfate (G418) and Zeocin. [source, 2016]
Sponge tamponades may be immersed in Antibiotic ointment (Bacitracin) or for example soaked Gentamicin solution [446]. [source, 2015]
Irrigation of the breast pocket and cleansing of the skin with a triple Antibiotic solution (Cefazolin, Bacitracin, and gentamycin) was performed before sewing in the graft. [source, 2015]
Overall, animals treated with NuPro had fewer lesions in the duodenum compared to the untreated ones, to a degree comparable to the group treated with the Antibiotic Bacitracin (Thanissery et al., 2010). [source, 2015]