Latest research on Aspirin

The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Acetylsalicylic acid also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Latest findings

Aspirin was given to the patients with thrombocytosis. [source, 2016]
Many NSAIDs like Ibuprofen, Aspirin [27], Flurbiprofen [28], Ketorolac [29, 30], and etodolac [31], have shown to produce a significant reduction in dental pain using clinical trials. [source, 2016]
Aspirin (Acetylsalicylic acid) was synthesized in 1897, and was included in the non-steroidal anti-inflammatory drugs (NSAIDs) commonly used for relieving the symptoms of inflammation and protecting against coronary heart disease [13,14]. [source, 2016]
In the past few decades, accumulating epidemiological evidence has suggested a promising chemopreventive role for Aspirin against various cancers [13,15]. [source, 2016]
Studies have revealed that Aspirin reduces the inflammation associated with several types of cancer, such as colorectal, breast, lung, prostate, esophageal, stomach, and ovarian cancers [13]. [source, 2016]
Aspirin is an inhibitor of cycloxygenase (COX)-2, thereby implying its use as a potential chemopreventive agent in breast cancer, which is accompanied by overexpression of COX-2 [16]. [source, 2016]
A large and diverse body of epidemiological evidence has been gathered from human studies on the potential chemopreventive effects of Aspirin use against breast cancer [15,17,18]. [source, 2016]
Recently, animal studies have also been conducted, which support breast cancer reduction with Aspirin treatment [19,20]. [source, 2016]
However, the gastrointestinal side effects, optimal doses, duration, and combination with other compounds should first be clarified for the use of Aspirin therapy in cancer prophylaxis. [source, 2016]
In this study, we investigated the anti-inflammatory and anti-cancer properties of Aspirin on 3T3-L1 adipocytes, 4T1 murine breast cancer cells, and their crosstalk. [source, 2016]