Latest research on Cialis

Tadalafil is an orally adminstered drug used to treat male erectile dysfunction (impotence). It is marketed worldwide under the brand name Cialis. It is a phosphodiesterase 5 (PDE5) inhibitor. Tadalafil's distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the "weekend pill." This longer half-life also is the basis of current investigation for tadalafil's use in pulmonary arterial hypertension as a once-daily therapy. [Wikipedia]

Cialis indications

Now introduced in 50 countries with multiple PDE5i formulations (tadalafil or Cialis, vardenafil or Levitra), patents expiring globally, and investigations for off-label use, such as in cardiovascular disease [4] or altitude sickness [5], [6], we may not only see an increase in the amount of PDE5i prescribed but also more long-term side effects surfacing as a result. [source, 2013]