Latest research on Eprex

Human erythropoietin (recombinant), produced by CHO cells.

Latest findings

In 2002, Johnson and Johnson issued 200,000 letters to health-care professionals in the US warning them of fake Procrit (erythropoetin) within one week of being notified of a severe counterfeit problem [31]. [source, 2005]
Formulation B consisted in a commercially available preparation (Eprex, CILAG AG, Switzerland) presented in pre-filled syringes containing 2000 IU rHuEPO, 0.15 mg polysorbate 80, 2.192 mg NaCl, 0.580 mg NaH2PO4.2H2O, 1.115 mg Na2HPO4.2H2O, 2.50 mg Glycine, and water for injection to complete 0.5 mL. [source, 2005]
In fact, two Eprex formulations with different stabilizers were pharmacokinetically equivalent [42]. [source, 2005]
Trimethyltin (TMT) chloride was purchased from Società Italiana Chimici. rhEPO (epoetin alfa, Procrit) was from Ortho Biotech. [source, 2003]
These cases do not appear to be associated with other preparations of epoetin alfa (Epogen, Procrit). [source, 2002]