Latest research on Fosamprenavir

Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.

Latest findings

Though there may be drug–drug interactions between HT and some protease inhibitors (PIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs), including Fosamprenavir (PI) and Efavirenz (NNRTI), newer antiretroviral agents likely do not possess the same pharmacologic concerns. [source, 2016]
Subject headings and keywords were tailored for each electronic resource using the following concepts: (atazanavir OR Darunavir OR dolutegravir OR Fosamprenavir OR Indinavir OR Lopinavir OR saquinavir) AND (Efavirenz OR enfuvirtide OR etravirine OR Lamivudine OR maraviroc OR Nevirapine OR raltegravir OR rilpivirine OR saquinavir OR Tenofovir OR tipranavir). [source, 2016]
At the time of presentation, the patient was taking Abacavir, Emtricitabine, and ritonavir-boosted Fosamprenavir for HIV and trimethoprim-sulfamethoxazole for prophylaxis. [source, 2015]
Rifabutin, Phenytoin, Efavirenz, cimetidine, esomeprazole, Digoxin, Fosamprenavir, Metoclopramide, Ritonavir, atazanavir, Tacrolimus, Cyclosporine, Sirolimus, Midazolam, Simvastatin, and other drugs that are metabolized by CYP3A4 are well-known drugs that interact with posaconazole. [source, 2015]
Fosamprenavir (FPV), an APV pro-drug, is used as a slow-release version of APV. [source, 2015]
Patients were treated with combinations of the following medications (n): Amprenavir (3), Indinavir (2), Delavirdine (2), Emtricitabine (2), Lamivudine (9), Abacavir + Lamivudine (2), enfuvirtide (2), saquinavir (2), Lopinavir + Ritonavir (11), FosAmprenavir (1), Nevirapine (6), Ritonavir (10), atazanavir sulfate (6), Abacavir plus Zidovudine plus Lamivudine (5), Tenofovir plus Emtricitabine (2), Didanosine (2), Tenofovir disoproxil fumarate (19), nelfinavir (4), Stavudine (3), and Abacavir sulfate (6). [source, 2015]
Calcium could be administered in the following formula (data obtained from the table POE_MED): Calcium, glucose Calcium, Calcium carbonate, Calcium Chloride, Calcium Chloride oral, Calcium gluconate, Fosamprenavir Calcium and Rosuvastatin Calcium. [source, 2015]
A 62-year-old male was found to be HIV infected in 2006; therefore, he started ART including Zidovudine 300 mg bid, Lamivudine 150 mg bid, Fosamprenavir 700 mg bid, and Ritonavir 100 mg bid. [source, 2015]
The efficacy, safety, and resistance profile of Fosamprenavir (FPV), the phosphate ester pro-drug of the protease inhibitor (PI) amprenavir, has previously been evaluated in HIV-infected ART-naïve and ART-experienced adults [1-5]. [source, 2015]
PIs currently available as liquid formulations/reconstituted oral suspensions for the treatment of paediatric patients in the United States include Fosamprenavir (aged 2 to 18 years) [12], coformulated RTV-boosted LPV (LPV/r) (aged ≥14 days) [13,14], nelfinavir (≥2 years) [15] and RTV-boosted Darunavir (DRV/r) (aged 3 to 18 years) [11,16]. [source, 2015]