Latest research on Gabapentin

Gabapentin (brand name Neurontin) is a medication originally developed for the treatment of epilepsy. Presently, gabapentin is widely used to relieve pain, especially neuropathic pain. Gabapentin is well tolerated in most patients, has a relatively mild side-effect profile, and passes through the body unmetabolized.

Latest findings

During the period when Oxycontin was used, Ibuprofen controlled-release capsules, carbamazepine, Gabapentin, and Alprazolam were utilized as adjuvant medications based on symptoms and clinical reactions (Table 1). [source, 2016]
Consistent with the observations in the present study of increased activation of ERK1/2 in compressed DRGs, it has been reported that p-ERK1/2 induces neuropathic pain in DRG neurons, and Gabapentin has an Analgesic effect by inhibiting the activation of ERK1/2 activation (44). [source, 2016]
They received beta blockers (n = 18), Primidone (n = 10), Topiramate (n = 3), octanol (n = 1), CLONAZEPAM (n = 3), Gabapentin (n = 3), Modafinil (n = 1), and Baclofen (n = 1). [source, 2016]
with AEDs, either Phenytoin (Phy, which blocks INaP) or Gabapentin (Gbp, mixed action resulting in potentiation of GABA transmission), is sufficient to reduce synchronicity towards the wildtype level. [source, 2016]
Gabapentin, antipain and isethionate were dissolved in water and added at concentrations of 0.2, 0.4 and 0.8 mg/ml, respectively. [source, 2016]
Though not statistically significant, those taking Clopidogrel, Gabapentin, Citalopram, Insulin, Hydrochlorothiazide, Metoprolol, Zolpidem, and Nitroglycerine were trending towards an increased risk of collision. [source, 2016]
Numerous other medications in this study were also trending towards an increased risk of motor vehicle collision, but were not found statistically significant included: Clopidogrel, Gabapentin, Citalopram, Insulin, Hydrochlorothiazide, Metoprolol, Zolpidem, and Nitroglycerin. [source, 2016]
Gabapentin, a newer anti-epileptic medication, is not known to affect driving ability, though it may. [source, 2016]
Common complaints regarding Gabapentin use include dizziness, nausea, and somnolence [35], which could affect one’s ability to drive. [source, 2016]
Previous studies showed an effect mainly for Levetiracetam on the PAS protocol, whereas most drugs did not affect this measurement, such as tiagabine, Diazepam, Lamotrigine, piracetam, Gabapentin, and Topiramate. [source, 2016]