Latest research on Levothyroxine

The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum of stimulatory effects on cell metabolism. [PubChem]

Levothyroxine and alcohol

A second logistic regression model was constructed with Levothyroxine as the dependent variable and factors potentially associated with Levothyroxine, including gender, race/skin color, education, per capita income (≤US$1245, US$1246-3319, and ≥US$3320), health insurance, and smoking (never, former or current) and alcohol use (never, past or current) as the independent variables. [source, 2015]
The exclusion criteria were as follows: The presence of an ocular disease that would prevent the examination of the corneal and retinal states, prior application of laser or any ocular surgery; a history of smoking or alcohol consumption; a history of any medication use within the previous 3 months, including hormonal therapy (except for Levothyroxine treatment) or systemic vasoactive drugs. [source, 2015]
We reviewed each patient’s medical file looking for the following comorbidities: BMI, diabetes, systolic left ventricular dysfunction (< 50%), statin use, Levothyroxine use, alcohol use (current vs. occasional vs. previous), smoking status (active vs. previous vs. life-long non-smoker), family history of polyps or colorectal cancer, personal history of inflammatory bowel diseases, polyps, colonic surgery, cholecystectomy, colorectal cancer or another neoplasia. [source, 2014]
The exclusion criteria were: Having undergone training or counseling sessions about sexual issues or marital relationships in the last month, having a history of medical illnesses or any physical, mental, and movement disabilities, being under treatment due to sexual dysfunction (lack or loss of libido, sexual aversion, lack of sexual pleasure, fearing of having sex, sexual motivation disorder, vaginal dryness, orgasmic dysfunction, painful intercourse, vaginismus, or extreme sexual stimulation), taking medications to increase or decrease libido (libido-enhancing drugs including Ephedrine, Caffeine, synarlyn, Levothyroxine, Danazol, herbal medicines like aphrodite and rose or damask rose fragrances, and libido-lowering medications such as Spironolactone, Hydrochlorothiazide, Clofibrate, Digoxin, Propranolol, Fluoxetin, Haloperidol, Clonidine, chlordiazepoxide, and methyl dopa), women with a history of aggression or sexual harassment, having undergone surgery in the past 6 months, having a mental illness, and drug use or alcohol consumption. [source, 2014]
Patients who met the following criteria were excluded from the study: history of anti-resorptive drugs use such as Bisphosphonates, Calcitonin, Raloxifene, history of estrogen replacement therapy during last five years, secondary osteoporosis due to the surgery or diseases such as diabetes, thyrotoxicosis, hyperparathyroidism, scleroderma, malabsorption syndromes and gastric surgery and drug induced osteoporosis due to immunosuppressive drugs, anticonvulsants drugs, Levothyroxin, Cyclosporine, Heparin or alcohol. [source, 2014]
Non-pharmacologic management includes: (1) strict glycemic control in patients with diabetes or impaired glucose metabolism; (2) treatment with Levothyroxine in patients with hypothyroidism; (3) avoidance (if possible) of medications that increase TG (such as beta-blockers or thiazide diuretics); (4) limitation or abstinence of alcohol; (5) avoidance of simple carbohydrates; (6) low fat diet (<30% of total daily caloric intake) and when TG level >1000 mg/dL, a very low fat diet (<15% of total daily caloric intake); and (7) weight loss in patients who are overweight or obese [1]. [source, 2013]
Other drugs that potentiate bleeding risk with warfarin are alcohol, Allopurinol, anabolic steroids, Amiodarone, selective serotonin reuptake inhibitors, Clofibrate, and to a lesser extent Gemfibrozil, antidiabetics, antimalarials, antiplatelets, anxiolytics, Disulfiram, Levothyroxine, and beta blockers like Propranolol. [source, 2010]
She denied smoking or alcohol intake and took no drugs except Levothyroxine irregularly. [source, 2005]
Vasospasm, in general, has been attributed to a variety of pharmacological stimuli ranging from Cocaine [11] and alcohol [12], to L-Thyroxine [13] and NSAIDs [14]. [source, 2004]