Latest research on Lorazepam

A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent. [PubChem]

Latest findings

In the 95 minutes before sedation, he received Morphine, Fentanyl, and Lorazepam intravenously. [source, 2016]
They received a mild anxiolytic (1.25–2.5 mg Lorazepam) and gastric protection (Pantoprazole 40 mg per os). [source, 2016]
In these studies, the effect sizes were comparable to those observed in analogous studies of intramuscular injection of antipsychotics or Lorazepam. [source, 2016]
A caveat is that Midazolam is chiefly used for sedation and has no antipsychotic effects; thus, like Lorazepam, it would not ameliorate hallucinations or delusions, and will not treat the underlying psychosis that may be engendering the agitation. [source, 2016]
Allowed concomitant medications included hypnotics (eg, Zolpidem or chloral hydrate), antiparkinson drugs, and Lorazepam. [source, 2016]
Since seizures in 10 (55.6%) out of 18 patients were not controlled by IV Lorazepam, other seizure medications such as Phenytoin were used. [source, 2016]
Participants who responded “Yes” to this question were asked to choose the drugs they had ever used from a list of 33 commonly used illegal drugs classified into nine categories (for example: inhalants, e.g. butane gas, bond, thinner, varnish, lighter gas; stimulants, e.g. Caffeine pills; tranquilizers, e.g. Valium, Ativan, Xanax; a large dose of antitussive, e.g. Luminar, Lubiking, Soma, Zinolta; diet pills, e.g. Lasix, Prion; marijuana; Hiropon; other hallucinogens, e.g. KETAMINE, LSD, Ecstasy, 5-MeO-DIPT, Kratom, Ice; opioid drugs, e.g. opiates, Morphine, Demerol, Nubaine; Cocaine). [source, 2016]
As examples, a person would reach the highest level of exposure in a 10 year period if he/she took any of the following for a total of 121 days or longer: Temazepam 15 mg/day, Triazolam 0.125 mg/day, or Lorazepam 2 mg/day. [source, 2016]
Medications with psychotropic activity were not allowed, with the following exceptions: Lorazepam for control of agitation, irritability, hostility, or restlessness; Zolpidem, Zaleplon, chloral hydrate, or Eszopiclone for insomnia; and Diphenhydramine, Benztropine, or Propranolol for EPS. [source, 2016]
Cyproheptadine was discontinued after 3 days and further occurrences of mild agitation and hypertension were treated with intravenous Lorazepam as needed. [source, 2016]