Latest research on Mometasone Furoate

Mometasone is a medium-potency synthetic corticosteroid with antiinflammatory, antipruritic, and vasoconstrictive properties. Studies in asthmatic patients have demonstrated that mometasone provides a favorable ratio of topical to systemic activity due to its primary local effect along with the extensive hepatic metabolism and the lack of active metabolites. Though effective for the treatment of asthma, glucocorticoids do not affect asthma symptoms immediately. Maximum improvement in symptoms following inhaled administration of mometasone furoate may not be achieved for 1 to 2 weeks or longer after starting treatment. he antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.

Mometasone Furoate indications

Controlled topical delivery of Mometasone Furoate to healing ethmoid Mucosa has been demonstrated to minimize adverse events and to promote healing after ethmoid ESS in a safe and effective fashion. [source, 2015]
Thus it is better to use Nasal steroid as it minimizes systemic side effects of corticosteroids especially with Mometasone Furoate, which is known by its low bioavailability. [source, 2015]
Mometasone Furoate and Fluticasone proprionate have been extensively studied in children, and no adverse effects on Cortisol levels, the hypothalamic-pituitary-adrenal axis or growth over 1 year have been detected,53 54 unlike beclamethasone. [source, 2015]
In the current investigation we compared the effects of Fluticasone furoate (FF) and Mometasone Furoate (MF) on the release of a pattern of Th1, Th2 and Th17 cytokines from human nasal polyp tissue. [source, 2014]
As an illustration, RLQ is applied to a biological example where the aim is to explore the effect of the steroid Mometasone Furoate (MF) in the proliferation of primary human lung fibroblasts. [source, 2013]
In this dataset, we investigated the time-course effect of the glucocorticoid Mometasone Furoate (MF) on primary human lung fibroblasts. [source, 2013]
The aim of the present study was to investigate the effects of Mometasone Furoate and Fluticasone furoate taken in the head down and forward position on hyposmia regarding the odor threshold (OT), odor discrimination (OD) and odor identification (OI) and final olfactory score (SDI) in the treatment of patients with persistent allergic rhinitis. [source, 2013]
To sum up, Mometasone Furoate and Fluticasone furoate have rather the same effects on hyposmia and on the classical symptoms of PER. [source, 2013]
Both Mometasone Furoate in MLE and Methylprednisolone aceponate were effective treatments for eczema. [source, 2013]
However, Mometasone Furoate in MLE showed superior efficacy, likely due to the effects of the physiological lipid mixture on enhanced skin barrier function. [source, 2013]