Latest research on Nexium

A highly effective inhibitor of gastric acid secretion used in the therapy of stomach ulcers and zollinger-ellison syndrome. The drug inhibits the H(+)-K(+)-ATPase (H(+)-K(+)-exchanging ATPase) in the proton pump of gastric parietal cells. [PubChem]

Nexium dosage

Notably, in one study, it was reported that the majority of patients with long-segment BE who received different dosages of esomeprazole (Nexium), a second-generation PPI, had an intra-gastric pH >4 for 81–88% of the day (the higher the dosage the longer the duration) (26). [source, 2015]
The toxicity profile of esomeprazole strontium was comparable to that of Esomeprazole Magnesium in a preclinical study, and no developmental toxicity was observed in a dose-ascending study examining its effects on embryo–fetal development.11 [source, 2015]
After discussion with their treating psychiatrist, two patients who had required intensive potassium repletion (including via ICU and PIC lines) were commenced on a low dose of Nexium as outpatients. [source, 2015]
Neither patient required intravenous potassium, although levels did fall intermittently (when patients omitted doses of Nexium). [source, 2015]
He received three treatments of chemoembolization, Octreotide, and high doses of Nexium at that facility. [source, 2011]