A highly effective inhibitor of gastric acid secretion used in the therapy of stomach ulcers and zollinger-ellison syndrome. The drug inhibits the H(+)-K(+)-ATPase (H(+)-K(+)-exchanging ATPase) in the proton pump of gastric parietal cells. [PubChem]
Nexium side effects
These data indicate that anemia and splengomegaly in cGKI-/- and cGKI rescue mice is caused by iron deficiency anemia due to intestinal blood loss and can be rescued by treatment with Esomeprazol.
Nexium is known to cause prolonged QT, and this is a risk for which patients would need to be monitored medically with regular ECGs.
In addition, gastrointestinal (GI) diseases account for substantial morbidity, mortality, and cost , which leads to the increased demand for the related drugs, such as Omeprazole capsules, Omeprazole enteric-coated tablets, EsOmeprazole Sodium for injection, and esOmeprazole magnesium enteric-coated tablets.