Latest research on Remicade

Tumor necrosis factor (TNF-alpha) binding antibody (chimeric IgG1). It is composed of human constant and murine variable regions. Infliximab is produced by a recombinant cell line cultured by continuous perfusion

Remicade dosage

Before 2 and 4 dose of Remsima mean PUCAI was 11 (0; 0-40) and 2 (0;0-5), respectively. [source, 2015]
A total of 56 patients diagnosed as having IBD [44 Crohn’s disease (CD) and 12 colitis ulcerosa (CU)] and treated with anti-TNFα agents (33 received adalilumab, 23 received Remicade) were evaluated by means of serum lipid profile and serum total cholesterol, triglyceride, LDL-c and HDL-c were measured within 1 month before the first dose of anti-TNFα agent and then after six-month periods. [source, 2015]
In total, 59 Remicade infusions were administered at home with a median dose of 369 mg (dose range: 300 to 700 mg). [source, 2015]
All currently existing anticancer therapies involving TNF are targeted towards the ligand, TNF itself, which includes administration of very high doses of exogenous TNF for melanoma treatment [14]–[16] or use of soluble receptors and/or various forms of TNF antibodies (Remicade, Humira) and a soluble TNF receptor fusion protein (Enbrel) [17], [18]. [source, 2014]
For the treatment of moderately to severely active UC, the recommended dose of Remicade (IFX; Schering-Plough Corporation, Kenilworth, NJ, USA) is 5 mg/kg given as an induction regimen at 0, 2, and 6 weeks, followed by a maintenance regimen of 5 mg/kg every 8 weeks thereafter. [source, 2014]
Based on earlier studies of TNFα neutralization in mice [26], we administered the anti-TNFα antibody infliximab (Remicade, Centocor Ortho Biotech, Malvern, PA) by intraperitoneal injection at 10 mg/kg body weight per dose. [source, 2012]
Therefore, infusions of infliximab (Remicade, Merck & Co.) were arranged and given as doses of 5 mg/kg at baseline, 2, 6 and 12 weeks. [source, 2012]
Remicade is administered by intravenous infusion (IV) in a physician's office; receipt of a single dose takes 2 to 4 hours. [source, 2009]
Her gastroenterologist indicated treatment with 3 doses of infliximab (5 mg/kg/day, Remicade, Schering-Plough, Kenilworth, NJ), but ocular signs did not improve. [source, 2008]