Latest research on solifenacin succinate

Solifenacin (rINN), marketed as solifenacin succinate under the trade name Vesicare, is a urinary antispasmodic of the anticholinergic class. It is used in the treatment of overactive bladder with urge incontinence. [Wikipedia]

solifenacin succinate interactions

She was under treatment with Paroxetine and solifenacin succinate. [source, 2015]
Under the urologist’s care, she was prescribed solifenacin succinate (5 mg/day) for 3 weeks, Oxybutynin chloride (5 mg/day) for 3 weeks, Fesoterodine fumarate (8 mg/day) for 3 months, and propiverine hydrochlroride (20 mg/day) for 4 weeks. [source, 2015]
A fixed-dose combination (FDC) tablet of Tamsulosin oral controlled absorption system (OCAS) 0.4 mg and solifenacin succinate 6 mg (Vesomni™, Astellas Pharma Europe BV, Leiden, the Netherlands) has been recently authorized for use in men with moderate-to-severe storage symptoms and voiding symptoms associated with BPH, not adequately responding to treatment with monotherapy. [source, 2015]
Complaining of severe symptoms, the patient had been treated with various anticholinergic agents (Cetriprin, Detrusitol, and Vesicare) with only periodical relief. [source, 2014]
Patients in group I (n = 84) received no treatment (control group) (C group), patients in group II (n = 85) received a daily oral dose of Tamsulosin 0.4 mg (T group), patients in group III (n = 84) received solifenacin succinate 10 mg (S group), and patients in group IV (n = 85) received a combination of the two medications once daily (T/S group). [source, 2013]
On the other hand, three new anticholinergic agents, solifenacin succinate, Tolterodine tartrate, and imidafenacin, were successively approved and marketed in recent years. [source, 2011]
The chemical name of solifenacin succinate is 1-azabicyclo [2.2.2] octan-8-yl (1s)-1-phenyl-3,4-dihydro-1h-isoquinoline-2-carboxylate Butanedioic acid. [source, 2011]
At the time of her visit to our pain clinic, she was receiving Propranolol HCl 20 mg, Mirtazapine 30 mg and Tramadol HCl 50 mg twice a day, along with Buspirone HCl 15 mg, solifenacin succinate 5 mg, Mefenamic Acid 250 mg, ethyl loflazepate 1 mg and sodium tianeptine 12.5 mg daily. [source, 2010]
The patient was receiving Propranolol, Mirtazapine, Tramadol, solifenacin succinate, Mefenamic Acid (category C; excretion into breast milk unknown), Buspirone HCl (category B; is not excreted in breast milk), ethyl loflazepate, and sodium tianeptine (not available). [source, 2010]
Although there are other medical alternatives such as Darifenacin, Trospium Chloride, and solifenacin succinate is available, their safety in children is not known. [source, 2010]